NIH R01 · 2025
PROJECT SUMMARY Sustained attention, the ability to focus on an activity or stimulus over time, is impaired in many brain disorders. Targeting attentional deficits for treatment is critical because these symptoms are negatively correlated with functional outcome and quality of life. Continuous performance tests (CPTs) have been designed to measure sustained attention in multiple species. Similar neural circuits are engaged in both humans and model organisms during CPT performance, supporting their use in translational studies that screen for novel therapeutics. The prelimbic cortex (PrL), is involved in both conflict detection and allocation of attention to cues before orientation,…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.