Carper Lab

San Diego State University

PSYCHOLOGY

San Diego · United States

NIH-funded
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NIH R01 · 2024

The Autistic Brain Over 45: The Anatomic, Functional, and Cognitive Phenotype

Project Summary Extremely little is known about neural and cognitive changes or long-term prognosis for adults with autism spectrum disorders (ASD) older than 50 years of age, although in the US alone hundreds of thousands of people with ASD will reach this age group in the coming decades. Cross-sectional findings suggest that new cognitive, sensorimotor, and mental health problems emerge and that accelerated brain tissue loss occurs. Functional and structural brain connectivity is also affected, as shown with resting state functional MRI and diffusion MRI. This project aims to characterize mid- to late-life trajectories of brain anatomy and function in ASD, as well as cognitive and…

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