NIH R01 · 2025
Noninvasive optical assessment of neuroprotection in deep hypothermic circulatory arrest procedures
PROJECT SUMMARY Neurologic dysfunction is a major concern for patients and clinicians as it significantly contributes to high morbidity and mortality, negatively affect patients’ quality of life and increase healthcare cost. Despite substantial technological advancements in surgery, cardiopulmonary bypass (CPB) and anesthesia, cardiac surgery carries substantially high incidence of neurologic dysfunction such as stroke, delirium and cognitive dysfunction. Aortic arch surgery involving partial or complete replacement of the aortic arch to treat aortic aneurysm and dissections is associated with the highest rates of neurologic dysfunction in cardiac surgery, assumed to be largely due to brain…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.