Carlson Lab

University of Minnesota

PEDIATRICS

Minneapolis · United States

NIH-funded
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Research focus

NIH R01 · 2024

Adult Cognitive and Neurobiological Indicators of Aging: Impact of Adversity and Social Support

Project Summary/Abstract Using a unique longitudinal data set and linear growth modeling analytic techniques, the proposed research will examine relations between early and life course trajectories of adversity and adult biobehavioral markers of aging. Animal and human studies suggest that early exposure to adversity may negatively impact developing biological systems altering long term structural and functional trajectories, and accelerating aging processes. The proposed research will examine this neurotoxicity hypothesis in relation to brain neurobiology (structure, function, connectivity) and related cognitive and epigenetic markers sensitive to adversity and aging. The research will…

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