NIH R01 · 2025
Systematic identification of cardiotoxic e-cigarette flavorants
Abstract The use of e-cigarettes (e-cigs) has increased substantially since they were first introduced in 2003. E-cig devices aerosolize e-liquids that typically consist of humectants with variable levels of nicotine and flavoring chemicals. Although there are thousands of commercially available flavor mixtures, they routinely overlap in individual flavor chemicals (flavorants), which are far fewer in number. Many of these flavorants belong to common chemical classes and are generally recognized as safe for ingestion. However, their direct and indirect cardiac effects following heating and inhalation, particularly in combination with nicotine, remain mostly unknown. Direct exposure to…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.