Carcea Lab

Rutgers Biomedical and Health Sciences

PHARMACOLOGY

Newark · United States

NIH-funded
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NIH R01 · 2025

Neuroendocrine circuits for engagement in affiliative social interactions

Engaging in affiliative social interactions predicts health and longevity. The hormone oxytocin, which is released by specialized neurons in the hypothalamus, has been shown to play an important role in affiliative behaviors. However, the mechanisms that control activity of oxytocin neurons and by which these neurons might then control engagement in social interactions, have not yet been elucidated. Our long-term goal is to dissect the neuroendocrine mechanisms driving voluntary engagement in affiliative social interactions. Our findings will facilitate the design of therapeutic interventions aimed at addressing the widening loneliness pandemic, as well as ASD. The objective of this grant…

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