Cao Lab

ST. Jude Children's Research Hospital

Memphis · United States

NIH-funded
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Research focus

NIH R01 · 2024

Understanding the developmental progression of subpallial neural progenitor cells

Project Summary The embryonic ventral telencephalon, the subpallium, is the developmental origin of numerous brain structures and cell populations such as the basal ganglia and cortical interneurons. These structures and cell populations are critical for higher brain functions and are often causally involved in neuropsychiatric disorders such as schizophrenia, autism, and drug addiction. Thus, a better understanding of ventral telencephalon development will not only improve our understanding of brain development and brain function but also advance treatments of nervous system disorders. All neurons and glia generated in the ventral telencephalon are descendants of subpallial neural…

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