Cannuscio Lab

University of Pennsylvania

FAMILY MEDICINE

Philadelphia · United States

NIH-funded
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NIH R01 · 2025

Increasing naloxone availability and use in high-risk settings: public libraries as partners for reducing opioid overdose mortality

PROJECT SUMMARY/ABSTRACT Opioid overdose mortality has increased substantially since the start of the COVID-19 pandemic. Opioid overdose deaths are preventable and can be reversed with the timely receipt of naloxone. To date, naloxone distribution and implementation programs have targeted traditional first responders (e.g., EMS) as well as people with opioid use disorder and their social networks. While these initiatives have resulted in measurable reductions in opioid overdose mortality, major gaps in naloxone availability and use persist. The overarching goal of this work is to save lives by advancing evidence regarding place-based naloxone implementation and overdose reversal readiness…

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