NIH R01 · 2025
The Hypothalamic Basis of Aging
ABSTRACT/SUMMARY Aging is multifaceted while many hormonal and metabolic regulators are crucial, pointing to the extremely strong significance of endocrine and metabolic processes in aging physiology and intervention. The hypothalamus is the “headquarters” for regulating systemic endocrine systems and metabolic physiology as well as the autonomic nervous system for physiological homeostasis. In the past, the lab of the PI has developed a major research area of studying the significance of hypothalamus in aging, including formulation of the “hypothalamic control of aging” paradigm which subsequently led to the generation of anti-aging model by hypothalamic stem/progenitor cells. The…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.