NIH R01 · 2025
Effects of Healthy Aging and Mild Cognitive Impairment on Memory Representations
Alzheimer’s Disease (AD) impairs not only cognitive abilities, such as memory, but also sensory functions, such as vision. The current project investigates memory-vision interactions in the early stage of AD known as amnestic Mild Cognitive Impairment (aMCI), as well as in healthy aging. We focus on memory for visual stimuli, which declines substantially in AD, predicting dementia more than a decade before diagnosis. We propose 3 functional MRI (fRMI) studies, each including 3 groups of participants: aMCI, older adults, and younger adults. Whereas most fMRI studies on memory and aMCI investigated memory processes, we focus on the quality of the information used by these processes or memory…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.