Amos Lab

Dartmouth-Hitchcock Clinic

Lebanon · United States

NIH-funded
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Research focus

NIH R01 · 2024

Optimizing colorectal cancer prevention: a multi-disciplinary, population-based investigation of serrated polyps using risk prediction and modeling

Project Summary/Abstract Colorectal cancer (CRC), the second most common cause of cancer deaths in the US, can be prevented through colonoscopy, during which potentially pre-cancerous polyps are removed from the colon. Serrated polyps may precede up to 30% of CRC, but unlike adenomatous polyps (their more common counterparts), there is limited data about their outcomes and natural history. Current clinical guidelines highlight that there is a critical lack of evidence available on future risks in patients with serrated polyps. To address this knowledge gap, this project proposes to combine the comprehensive data on colonoscopy patients, procedures, and pathology of the New Hampshire…

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