Burstein Lab

Beth Israel Deaconess Medical Center

Boston · United States

NIH-funded
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NIH R01 · 2024

Narrow Band Green Light Effects on Cortical Excitability and Responsivity in Migraine

ABSTRACT Significance: Exposure to narrow band green light (nbGL) appears to reduce intensity, frequency, and duration of migraine headache and some of its most bothersome symptoms and does so more effectively than exposure to dark. Because many migraine characteristics are attributed to abnormal cortical hyperexcitability and responsivity, we are seeking to determine whether nbGL attenuates cortical activity, and if so to what extent, what extent it differs from dark (known to help migraine headache). Given that pain and emotional changes are major components of migraine, we will assess cortical activity including functional connectivity in a translational study design. A rodent model will…

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