NIH R01 · 2024
Narrowing the mechanistic gap for anterior prefrontal cortex function
PROJECT SUMMARY Prefrontal cortex (PFC) is a large and heterogeneous brain area comprising the front third of the human brain that has been implicated in numerous mental health disorders. One of the least-studied subregions of PFC is anterior lateral PFC (aLPFC). This region, whose functioning is impacted in disorders like schizophrenia, has been implicated in reasoning, multi-tasking, planning, memory monitoring, decision-making, and more. It behooves us to reach a mechanistic understanding of the fundamental processes subserved by this region; however, there are numerous challenges, including the absence of a precise animal model, inconsistencies regarding terminology and anatomical…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.