Bruxvoort Lab

Research focus

NIH R01 · 2025

Determining the impact of peer-led community-based PrEP delivery among youth in Brazil: A randomized controlled trial

SUMMARY/ABSTRACT HIV is declining in many parts of the world, but rising in Latin America, including Brazil. From 2010 to 2019, the number of new HIV infections in Latin America increased 21%, compared to a global reduction of 23%. The number of reported HIV cases in Brazil increased from 13,719 in 2011 to 40,880 in 2021, with increases driven by youth aged 15-24 years. Among men aged 15-24 years, HIV incidence per 100,000 increased from 37.8 in 2000 to 66.5 in 2018 – a 75% increase. HIV pre-exposure prophylaxis (PrEP) was approved in Brazil in 2021 for adolescents aged 15-17 years, but PrEP uptake has been <1% among youth. Our team conducted the first and largest PrEP demonstration study…

From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.