NIH R01 · 2025
Epigenetics, air pollution, and childhood mental health
Project Summary Anxiety and depression are among the most debilitating disorders worldwide and increase the risk for later-life adverse health outcomes including chronic anxiety and depression, substance abuse and suicide. Anxiety and depression are also the most common psychiatric disorders among adolescents with symptoms presenting as early as 4-5 years of age. Yet, we still have a poor understanding of the etiology of anxiety and depression in youth and the mechanisms involved. Air pollutants are widely recognized for their ability to affect the central nervous system and adversely impact neurodevelopment during childhood. The epigenome is particularly sensitive to environmental stimuli…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.