NIH R01 · 2024
Towards personalized medicine: pathophysiologic contributions to post-stroke sleep apnea
Abstract Stroke is the leading cause of adult disability in the US, a top killer of Americans, and impacts Mexican Americans (MAs) to a greater extent than non-Hispanic whites (NHWs). One opportunity to improve stroke outcomes and reduce disparities may exist through identification and treatment of obstructive sleep apnea (OSA) in individuals with stroke. OSA in the general population is heterogeneous with respect to pathophysiology, expression of disease, response to therapies, and association with outcomes. Mechanistic causes of airway collapse during sleep can be categorized from polysomnography (PSG) data as OSA endotypes, including an anatomic cause (collapsibility), and 3 non-anatomic…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.