Brown Lab

North Carolina State University Raleigh

ENGINEERING (ALL TYPES)

Raleigh · United States

NIH-funded
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NIH R01 · 2024

Anti-microbial platelet-like-particles to treat internal bleeding and augment subsequent healing

PROJECT SUMMARY Uncontrolled bleeding following trauma represents a significant clinical problem; exsanguination is the major cause of death in both civilian and battlefield traumas. If hemostasis is achieved, wound repair following trauma can be impeded by several complications including infection, keloid formation, insufficient blood flow and a compromised immune system. Traumatic brain injury (TBI) also frequently occurs concurrently with hemorrhage following trauma and is associated with high risks of infection. Infections are a leading cause of mortality, morbidity, and economic disruption around the world, highlighting the need for better methods to achieve hemostasis and improve…

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