NIH R01 · 2024
Genome-wide assessment of transcriptional state history
PROJECT SUMMARY The accurate description of cellular states—be it on the genomic, transcriptomic, or proteomic level—has been a major driver in the disentanglement of nature’s mysteries. Mainly supported by technological advances such as next-generation sequencing or single-cell technologies, we now can describe the distinct cellular populations within a tissue or collection of cells in intricate detail. This allows us to understand health and disease, and it often proves instrumental in our ability to develop effective treatments. However, our current technologies are mostly geared toward an understanding of current cellular states. While various technologies can trace the lineage of…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.