NIH R01 · 2024
Applying Genomic Dosimeters of UV Damage to Predicting Skin Cancer Risk
Project Summary Cancer prevention programs can reduce cancer incidence, cancer-related deaths, and healthcare costs. Yet population-level cancer prevention programs are expensive and difficult to implement, and their benefit must be weighed against the risk of overdiagnosis and harms associated with followup care. An emerging view is that prevention efforts ought to be focused on the populations at highest risk. In an era of precision medicine, Precision Prevention would objectively measure a person's past exposure to a risk factor in order to predict that person's risk of cancer or occupational disease. High-risk individuals would then be monitored frequently by a specialist. Skin cancers…
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