NIH R01 · 2025
Project Summary Clinical testing for peripheral auditory dysfunction focuses on the audiogram. However, many auditory perceptual deficits, such as tinnitus, hyperacusis, and difficulty with speech perception, cannot be fully explained by the audiogram. Cochlear deafferentation (i.e., loss of inner hair cells, spiral ganglion cells, or cochlear synapses), may contribute to these perceptual problems. However, there is currently no method for diagnosing deafferentation in living humans. This prevents us from determining the prevalence of deafferentation in humans, identifying deafferentation risk factors and perceptual consequences, or testing potential drug treatments. Several non-invasive…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.