Brady Lab

University of Vermont & ST Agric College

SURGERY

Burlington · United States

NIH-funded
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NIH R01 · 2025

The Development of Clinically-Motivated and Explainable Machine-Learning-Based Image Classifiers to Detect Trachoma

PROJECT SUMMARY/ABSTRACT Trachoma is the leading infectious cause of vision loss worldwide, and one of the most important causes of irreversible blindness, afflicting people in some of the world’s poorest regions. Global efforts to eliminate trachoma have led to substantial reductions in prevalence in some areas, but new tools are needed to achieve elimination and monitor for disease reemergence post-elimination. The current method of identifying active trachoma (for which the key sign is trachomatous inflammation—follicular (TF)) requires in-person assessment by a grader who has been appropriately standardized against an internationally-certified reference expert. Unfortunately, as…

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