Bradley Lab

Magee-Women's Res Inst and Foundation

Pittsburgh · United States

NIH-funded
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NIH R01 · 2024

A Randomized Pilot and Feasibility Study of a cultuRE-Directed approach to Urinary traCT Infection symptoms in older womeN: a mixed methods evaluation - the REDUCTION trial

PROJECT ABSTRACT Urinary tract infections (UTIs) account for significant morbidity on both an individual and societal level. UTIs are especially common in older women and a subset are prone to recurrent UTIs (rUTIs). Current understanding of the natural progression of patient reported UTIs in older women with rUTI is limited due to low levels of inclusion in previous randomized controlled trials on initial non-antibiotic strategies. For Aim 1: We seek to evaluate the feasibility of recruiting eligible participants into a randomized trial of a culture-directed versus empiric antibiotic strategy for patient-reported UTI symptoms in older women and the adherence to study procedures. We will…

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