Bradley Lab

Pennsylvania State Univ Hershey Med Ctr

INTERNAL MEDICINE/MEDICINE

Hershey · United States

NIH-funded
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NIH R01 · 2025

SHePREG: Study of Heart function in PRE-Eclampsia during and after PreGnancy

Project Summary/Abstract Advances in medicine and science have led to improved health in women, yet hypertensive disorders of pregnancy such as pre-eclampsia (PreE) remain one of the reasons that maternal cardiac disease is a leading cause of pregnancy-related death in the United States. In this project we examine the impact of severe PreE on human heart function in women from diverse racial (Non-Hispanic/Black, Non-Hispanic/White, Hispanic, South/Southeast Asian) backgrounds. We will evaluate heart function at time of delivery, and at 6- and 12- months postpartum. Our pilot data demonstrates that women with severe PreE have evidence of persistent heart dysfunction up to 3 months after…

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