Boyne Lab

University of Cincinnati

PHYSICAL MEDICINE & REHAB

Cincinnati · United States

NIH-funded
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NIH R01 · 2025

High-Intensity Interval Training to Recover Walking Post-Stroke: HIT-Stroke Trial 2

PROJECT SUMMARY / ABSTRACT Among the 7 million stroke survivors living in the U.S., fewer than 10% have adequate walking speed and endurance to complete normal daily activities like grocery shopping, which leads to a loss of life roles. Stroke rehabilitation guidelines recommend moderate-intensity aerobic training (MAT) via walking exercise to address this limitation in walking capacity. However, recent evidence suggests that MAT may have negligible effects among many people in the chronic phase of stroke (>6 months post stroke), especially those with severe gait impairment (speed <0.4 m/s). There is growing belief that a more vigorous training intensity (>60% heart rate reserve vs 40-60%)…

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