Boyer Lab

Oregon Health & Science University

OBSTETRICS & GYNECOLOGY

Portland · United States

NIH-funded
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NIH R01 · 2024

The impact of enculturation on the epigenetic relationship between chronic stress and hypertension in Yup'ik Alaska Native people

Project Summary The objective of the proposed research is to identify molecular mechanisms linking the protective role of culture to blood pressure regulation, a major risk factor for stroke in Yup'ik Alaska Native people. The prevalence of stroke is higher among American Indian and Alaska Native (AIAN) populations than in any other U.S. racial/ethnic group. Chronic psychological stress increases the risk for hypertension, and is the most frequently cited stroke risk factor in AIAN populations. The prevalence of stroke has increased over the past 25 years, and is likely brought on by chronic stressors including historical trauma, cultural change and adverse socioeconomic conditions which,…

From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.

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