Boyce Lab

Univ of North Carolina Chapel Hill

INTERNAL MEDICINE/MEDICINE

Chapel Hill · United States

NIH-funded
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NIH R01 · 2025

After the flood: Optimal strategies to prevent malaria epidemics caused by severe flooding

The increasing frequency of weather extremes such as flooding on the incidence of malaria and other vector-borne diseases is an issue of substantial public health importance. Therefore, there is an urgent need to develop effective mitigation and control strategies. In May 2020, we piloted a post-flood malaria chemoprevention intervention in rural western Uganda. When compared to two neighboring villages where no intervention was deployed, we estimated a 53% reduction (aRR 0.47, 95% CI 0.34 – 0.62, p<.01) in malaria incidence in the six months post-intervention. Building on these results, the scientific aim of this proposal is to evaluate the effectiveness of a targeted, time-limited malaria…

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