NIH R01 · 2025
Newborns have immature liver function that is inefficient at metabolizing bilirubin. Consequently, nearly 80% of preterm and 60% of term babies develop hyperbilirubinemia resulting in neonatal jaundice within a week of birth. Severe hyperbilirubinemia can be fatal, making early, frequent, and accurate monitoring of bilirubin vital to avoid severe health issues and determine appropriate treatment. The gold standard for detecting hyperbilirubinemia is an invasive blood test to measure total serum bilirubin (TSB); however, frequent blood sampling in neonates is costly, painful, and increases the risk of infection. Existing non-invasive methods to monitor hyperbilirubinemia lack sufficient…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.