NIH R01 · 2025
Improving Diagnostics and Neurocognitive Outcomes in HIV/AIDS-related Meningitis
ABSTRACT Central nervous system (CNS) infections are common across all ages in Africa in people with or without HIV-infection. In people with HIV, cryptococcal meningitis has historically been the second most common AIDS-defining illness in Africa and the most common cause of adult meningitis in Africa overall. The next most common cause of meningitis is likely TB meningitis, although CSF diagnostics are challenging. With the widespread availability of antiretroviral therapy (ART), long term survival in persons living with AIDS and CNS infections should be possible, but delayed or inaccurate diagnoses and limited therapeutic options contribute to poor outcomes. In the era of widespread ART…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.