Bouchareb Lab

Temple Univ of the Commonwealth

INTERNAL MEDICINE/MEDICINE

Philadelphia · United States

NIH-funded
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NIH R01 · 2025

Platelet-mitochondria transplantation to treat mitochondrial dysfunction in acute kidney injury

(PLEASE KEEP IN WORD, DO NOT PDF) This project responds directly to PAR-21-038; the PI changes direction from valvular heart disease to study acute kidney injury (AKI). Indeed, the PI is a new faculty member in the Division of Nephrology, Department of Medicine. The PI will apply her previous expertise in platelet structure to examine a new therapeutic approach to deliver mitochondria to injured kidneys and therefore stop the progression of AKI to end-stage renal disease. The PI is working closely with Dr. Daehn, an expert in kidney disease and mitochondrial function. In addition, she will be collaborating with Dr. Brestoff, an expert in mitochondria transplantation, to validate the…

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