NIH R01 · 2025
Volitional Control of the Nonhuman Primate Lower Limbs
SUMMARY The ability to modify ongoing gait with precise, voluntary adjustments is what allows animals to navigate complex terrains and to execute skilled actions during ongoing pursuits. However, how the nervous system generates the signals to precisely control the lower limbs while simultaneously maintaining ongoing locomotion is still poorly understood. While there is some consensus in the role of spinal cord (SC) central pattern generators (CPGs) in the maintenance of locomotion, little is known about the role of primary motor cortex (M1), especially in the case of volitional adjustments to ongoing locomotion movements. Our own work suggests that M 1 plays at least a dual role in both…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.