NIH R01 · 2025
Vitamin K and D and Cognitive Impairment in Older Adults
PROJECT SUMMARY Identification of dietary factors that delay decline in cognitive function has important implications for reducing the burden of Alzheimer’s dementia (AD) and reducing health care costs as the population ages. Inadequate intakes of vitamin K and vitamin D are common among the elderly, and there is growing evidence that both nutrients have biological roles in the pathogenesis of Alzheimer’s disease (AD) and related pathologies, and the risk of Alzheimer’s dementia. We demonstrated in the Rush Memory and Aging Project (MAP) study that higher postmortem brain levels of vitamin K and vitamin D were associated with better cognitive function prior to death. Further investigation…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.