Boehnke Lab

University of Michigan at Ann Arbor

BIOSTATISTICS & OTHER MATH SCI

Ann Arbor · United States

NIH-funded
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NIH R01 · 2025

Identifying Genes for Type 2 Diabetes: FUSION

Project Summary / Abstract Type 2 diabetes (T2D) is a major cause of morbidity and mortality, affecting >450M people worldwide and >34M in the US alone; >26% of Americans aged ≥65 years have T2D. T2D incidence and prevalence are increasing rapidly. In the US, direct medical costs of diabetes in 2017 were estimated at $237 billion, ~15% of all US health-care costs. The goals of the Finland-United States Investigation of NIDDM Genetics (FUSION) study are to identify genetic variants, genes, and mechanisms that influence T2D risk and variability in T2D- related quantitative traits (QTs), and to foster clinical translation of these findings. Improved understanding of the genetic bases of T2D…

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