Boas Lab

Boston University (Charles River Campus)

ENGINEERING (ALL TYPES)

Boston · United States

NIH-funded
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NIH R01 · 2024

Neurophotonic Advances for Mechanistic Investigation of the Role of Capillary Dysfunction in Stroke Recovery

ABSTRACT Neuroimaging methods are invaluable for managing the treatment of stroke patients in the acute phase of guiding reperfusion and salvaging tissue, and are being used more and more to understand the effect of and ultimately guide treatments in the chronic phase of functional brain recovery. At least some degree of functional recovery is widely observed in most patients in the months following stroke. The exact biological mechanism directing this recovery is under active investigation. BOLD functional Magnetic Resonance Imaging (fMRI) and functional Near Infrared Spectroscopy (fNIRS), both of which non-invasively measure the vascular response to brain activity, are valuable tools for…

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