NIH R01 · 2024
Role of translational fidelity in cellular physiology of oral streptococci
ABSTRACT Ribosomes are composed of ribonucleoproteins and are essential for protein biosynthesis, which is one of the most complex biological processes in the cell. In prokaryotes, mature ribosomes contain proteins (r- proteins) and RNA (rRNA) that are assembled into the mature 70S ribosome. The 70S ribosomes are made by two subunits, designated as the 30S (small) and the 50S ribosome (large) subunits. The small subunit is composed of the 16S ribosomal RNA (rRNA) and over 20 core r-proteins while the large subunit is composed of 23S and 5S rRNAs, and more than 30 core r-proteins. Ribosome is not a stationary entity, rather it is adapted to changing environments giving rise to ribosome…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.