Biswal Lab

University of Wisconsin-Madison

RADIATION-DIAGNOSTIC/ONCOLOGY

Madison · United States

NIH-funded
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NIH R01 · 2025

Novel PET/MR Imaging Approach for Persistent Postsurgical Pain Following Joint Replacement

Project Abstract Overview: This project aims to develop a reliable 18F-fluorodeoxyglucose (18F-FDG) PET/MRI method with novel metal artifact correction techniques to provide early identification of prosthetic complications causing persistent postsurgical pain (PPSP) following total hip arthroplasty (THA). Relevance: THA is one of the most rapidly growing procedures to treat the end-stage hip joint pain and dysfunction, and its annual cases are estimated to reach 572,000 by 2030. Unfortunately, a substantial number of patients experience PPSP after the procedure, which, without proper treatment, can significantly impair the quality of life. However, the early identification of pain…

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