NIH R01 · 2025
Excess cardiovascular inflammation in TB and HIV: EXFIN-TB
TB is the leading global killer among infectious diseases and the number one cause of death among those with HIV. Furthermore, the estimated 9 million TB survivors completing treatment each year have a 3-fold increased risk of death from any cause when compared to those without previous TB. While post-TB lung disease is a major contributor to the long-term morbidity and mortality faced by TB survivors with and without HIV coinfection, cardiovascular disease accounts for a greater proportion of post-TB deaths than pulmonary disease. Moreover, epidemiologic studies have found that adults with a history of previous TB have a ~50% increased risk of cardiovascular events. Importantly, many…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.