Birmaher Lab

University of Pittsburgh at Pittsburgh

PSYCHIATRY

Pittsburgh · United States

NIH-funded
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Research focus

NIH R01 · 2024

Predicting Recurrences in Bipolar Illness (Prompt-BD)

With each recurrence, the prognosis for Bipolar Disorder (BD) worsens and the risk for suicidality and substance abuse increases, indicating the need to identify and manage the factors associated with recurrence risk. Factors associated with recurrence risk for the group as a whole have been identified, however, the question of how to predict recurrence risk for an individual with BD remains unanswered. Since the course of BD is heterogenous, the ability to predict recurrence risk at the person level would allow treatment to be tailored to the specific individual. As in other fields of medicine, we developed a risk calculator (RC) that predicts with approximately 80% discrimination the 1-5…

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