NIH R01 · 2024
ABSTRACT Assembly of the brain relies upon spatiotemporally coordinated action of a small number of intracellular signaling pathways, which together govern an astonishingly wide array of processes, ranging from cell differentiation to tissue morphogenesis. How a handful of pathways can provide the precision and specificity required for the emergence of complex tissue structure and function that unfold over long periods of time, such as those of the human brain, has been a long-standing question in developmental biology. Even though landmark studies in developmental genetics, biochemistry and synthetic biology over the last decades have uncovered the working mechanisms of many signaling…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.