Birch Lab

Retina Foundation of the Southwest

Dallas · United States

NIH-funded
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Research focus

NIH R01 · 2025

Binocular Vision, Amblyopia, and Refractive Development

Amblyopia is a common disorder of neurodevelopment resulting from discordant binocular visual experience during the first years of life, affecting 2-3% of children. Randomized clinical trials (RCTs) show that current approaches to amblyopia treatment, most often patching the fellow eye, are effective in improving visual acuity. However, full recovery occurs in less than 50% of children. Standard-of-care patching treatment of amblyopia is effective but suffers from poor adherence, exhibits significant individual differences in response even when adherence is good, and fails to address the binocular dysfunction that is fundamental to amblyopia. There is a need for an alternative approach to…

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