NIH R01 · 2024
Multiscale Models for Predicting Short and Long-term Outcome of Cardiac Resynchronization Therapy
Project Summary Heart failure is associated with an annual mortality rate of 300,000 Americans, while over a million experience a myocardial infarction. Many patients with both heart failure and myocardial infarction also develop ventricular dyssynchrony, which exacerbates cardiac dysfunction and worsens symptoms. Cardiac resynchronization therapy (CRT) has emerged as an effective therapy for patients who suffer from heart failure and dyssynchrony, such as left bundle branch block (LBBB). When CRT is successful, it improves survival by stopping and even reversing the progression of heart failure. CRT immediately restores electrical and mechanical synchrony of the healthy myocardium, and…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.