NIH R01 · 2024
The role of late life depression in cognitive decline and Alzheimer's Disease risk
The role of late life depression in cognitive decline and Alzheimer’s Disease risk Abstract The risk of developing Alzheimer’s Disease increases by three-fold for people who experience symptoms of depression in older age. Therefore, depression is thought to be a modifiable risk factor or early indicator of Alzheimer’s Disease. Yet, the link between depression and Alzheimer’s Disease is poorly understood. The aim of this administrative supplement to parent R01 MH128286 is to elucidate the link between depression and Alzheimer’s Disease. In Aim 1, we will identify brain mechanisms that are shared between depression and cognitive decline in older age. In Aim 2, we will determine the pathway…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.