NIH R01 · 2024
Multimodal brain imaging of the neural effects of methylphenidate in patients with ADHD
There is continued interest to develop novel pharmacological treatments for attention deficit hyperactivity disorder (ADHD), in part because of its high prevalence in the community, and lack of optimal response to current medications, including intolerable side effects. Central nervous system (CNS) pharmacodynamic (PD) measures have not been well characterized in pediatric and adolescent populations, which is important for future drug development. Brain imaging tools are ideal CNS PD measures in children because they are non-invasive and reproducible. Our goal is to understand the neural correlates of treating ADHD with methylphenidate, specifically in children and adolescents. First, we…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.