Bickford Lab

University of Louisville

ANATOMY/CELL BIOLOGY

Louisville · United States

NIH-funded
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NIH R01 · 2025

The Influence of the Pretectum on the Visual Thalamus

PROJECT SUMMARY / ABSTRACT The pretectum (PT) is a relatively unexplored brain area in mammals, and it is currently unknown how the PT affects the visual properties of thalamic neurons that underly the complex integration of vision and movement. Here, a team of investigators propose a multifaceted approach - from synapse to behavior – to answer fundamental questions regarding PT circuits (Aim 1), the visual and/or motor response properties of identified PT neurons (Aim 2), the effects of PT input on the response properties of thalamic neurons (Aim 3), and the effects of the PT on visual behavior (Aim 4). Each aim will utilize a combination of novel intersectional circuit labeling…

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