NIH R01 · 2024
PROJECT SUMMARY / ABSTRACT Timely diagnostics for fungal infections are sorely needed to guide effective therapy. Invasive fungal infections are increasing in prevalence, causing millions of deaths each year worldwide, and drug resistance poses a rising threat. Due in large part to slow, outmoded diagnostics that require days of culture to identify the pathogen and report its antifungal susceptibility profile, mortality from invasive fungal infections can exceed 40%. This in turn leads clinicians to rely on empiric and prophylactic use of antifungals that may be ineffective, cause needless toxicity, and select for resistance. Rapid precision diagnostic assays are critically needed to…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.