NIH R01 · 2025
Project Summary Individuals who suffer from post-traumatic stress disorder (PTSD) are often at higher risk for developing comorbid alcohol use disorder (AUD). Studying individual differences in response to stress is important as not everyone who experiences trauma or witnesses a traumatic event develops PTSD. In preclinical models, exposure to the scent of a predator is commonly used for the study of PTSD-like phenotypes. During the current funding period and in this renewal we use exposure to 2,5-dihydro-2,4,5-trimethylthiazoline (TMT) a synthetically derived component of fox feces as the predator odor stressor. We find individual differences in stress reactivity specifically in the…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.