Bertrand Lab

Boston University Medical Campus

INTERNAL MEDICINE/MEDICINE

Boston · United States

NIH-funded
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NIH R01 · 2025

Socio-environmental context in monoclonal gammopathy of undetermined significance (MGUS)

African Americans have a more than 2-fold higher incidence of multiple myeloma (MM) and its asymptomatic precursor condition, monoclonal gammopathy of undetermined significance (MGUS) compared to individuals from other racial/ethnic groups. However, the etiological factors for MGUS/MM are not known and few epidemiologic resources are currently available to support research in high-risk populations. Notably, there is little evidence that genetic factors explain these differences; differences in prevalence of MGUS and MM among population groups may thus reflect external lifestyle and other factors. We posit that these population differences are reflected in individual-level financial and…

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