Bergouignan Lab

University of Colorado Denver

INTERNAL MEDICINE/MEDICINE

Aurora · United States

NIH-funded
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NIH R01 · 2024

Breaking up sedentary behaviors to improve glucose control in a population at risk for developing type 2 diabetes

PROJECT SUMMARY/ABSTRACT Newly released guidelines recommend increased physical activity (PA) and reduced sedentary behaviors (SB) to improve glycemia and prevent the onset and progression of type 2 diabetes (T2D). Typically, 30-60 min bouts of PA are advocated per day. Although this approach increases PA, it does not decrease the length of the sedentary periods through the day. This is important because recent epidemiological data suggest that frequently interrupting sedentary time improves glucose control even in people who achieve the recommended levels of PA. Our preliminary experimental data suggest that breaking up prolonged sedentary time by performing multiple short bouts (5 min) of…

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