NIH R01 · 2025
SUMMARY Traumatic peripheral nerve injuries (PNI) lead to functional loss and incomplete recovery of peripheral nerve function while also impacting the corresponding brain regions that receive, process, and send out signals to and from the affected nerves. A prolonged duration of denervation due to PNI have adverse implications for both the nerve's prognosis and the associated brain regions. Over time, the absence of normal nerve signaling can cause corresponding brain regions to adapt to the loss, making reintegration more challenging after nerve recovery. This long-term disconnection between the nerve and brain can lead to motor and sensory skill impairments that require retraining that…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.