NIH R01 · 2024
Impaired sensory filtering as a mechanism of Parkinson's disease
PROJECT SUMMARY Conventional models of Parkinson’s disease (PD) dysfunction do not account for sensory feedback, which is both clearly represented in the basal ganglia and clearly impaired in PD. Despite the critical importance of this feedback to normal movement, the contribution of impaired sensory processing to PD pathophysiology is unknown. Our long-term goal is to clarify the role of sensory feedback in the production of pathological motor commands in PD. This research could help reveal the neural basis of both PD pathology and its treatment, leading to more efficient clinical practices, driving the development of novel therapeutic technologies, and helping to alleviate the enormous…
From the public funding record at NIH RePORTER. Describes the funded project, not the reviews below.