Benitez Lab

Beth Israel Deaconess Medical Center

Boston · United States

NIH-funded
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NIH R01 · 2025

Multi-tissue High-throughput Proteomic and Genomic Study in Parkinson's Disease

Project Summary/Abstract Parkinson's disease (PD) is the most common neurodegenerative movement disorder, affecting more than 6 million people worldwide, with the prevalence projected to double in the next few decades. Despite the improvements in high-throughput genomics and proteomics that have significantly facilitated the advancement of biomarker discovery in other neurodegenerative diseases, there are no reliable biomarkers for PD. Currently, the PD diagnosis relies almost entirely on clinical examination. There are several reasons for the lack of reliable biomarkers in PD including most studies have been focused on single molecules in one tissue, small samples sizes and a lack of…

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